Press release
Please fill in this form and return it to graduateschoolhealth@au.dk in Word format no later than three weeks prior to your defence.
Basic information
Name: Andreas Gravgaard Andersen Email: andreasga22@gmail.com Phone: +45 3165 8140
Department of: Medical Physics
Main supervisor: Ludvig Muren, professor,
Dept. of Clinical Medicine and Danish Centre for Particle Therapy Title of dissertation: Strategies for evaluating and improving proton plan robustness towards inter-fractional organ motion
Date for defence: Friday, April 29th 2022 at (time of day): 10 AM Place: Aarhus University Hospital, Palle Juul-Jensens Boulevard 99,
Entrance C, level 1, Auditorium C114-101, DK-8200 Aarhus N.
Press release (Danish)
Strategies for evaluating and improving proton plan robustness towards inter-fractional organ motion
Protonbehandling kan spare sundt væv omkring en tumor bedre sammenlignet med konventionel røntgenstrålebehandling (RT). Protoners dosisfordeling er følsom over for tæthedsændringer i bestrålingsretningen. Robust planlægning kan bruges til at tage højde for potentielle ændringer, før behandling starter. Derudover er det nødvendigt at overvåge patientens anatomi under hele
behandlingen. En kombination af disse to strategier kan muliggøre behandling af et mere omfattende spektrum af kræftindikationer.
En samling af forskellige tilgange til at redegøre for inter-fraktioneret bevægelse i protonterapi er blevet undersøgt. Specifikt handler det om analyse af strålevinkelens robusthed over for dosis og områder og tilvejebringelse af hurtige og pålidelige metoder til overvågning af indflydelsen af interfraktionelle ændringer på dosisplanen.
Et ph.d.-projekt fra Aarhus Universitet, Health. Projektet er gennemført af Andreas Gravgaard Andersen, der forsvarer det 2022/04/29
Pressemeddelelsen - afsluttes med:
Forsvaret af ph.d.-projektet er offentligt og finder sted den 29. April kl. 10 i XX auditorium, Aarhus Universitet, Vejnavn, By. Titlen på projektet er ”Strategies for evaluating and improving proton plan robustness towards inter-fractional organ motion”. Yderligere oplysninger: Ph.d.-studerende Andreas Gravgaard Andersen, e-mail: andreasga22+au@gmail.com, tlf. +45 3165 8140.
Bedømmelsesudvalg:
Professor Michael Robert Horsman (chairman and moderator of the defence) Department of Oncology (EKO), Aarhus University Hospital, Aarhus, Denmark Professor, Dr. Katia Parodi
Faculty of Physics, Ludwig Maximilians Universität, München, Germany Chief physician, Ph.D. Peter Meidahl Petersen
Department of Oncology, Rigshospitalet, Copenhagen, Denmark Press release (English)
Strategies for evaluating and improving proton plan
robustness towards inter-fractional organ motion
Proton therapy can better spare healthy tissue around a tumour compared to conventional X-ray radiotherapy (RT). However, the proton dose distribution is sensitive to density changes in the beam path. Robust planning can be used to account for potential changes ahead of treatment. Additionally, it is necessary to monitor the patient anatomy throughout treatment.
A combination of these two strategies may allow treating a more comprehensive range of cancer indications.
A collection of different approaches to account for inter-fractional motion in proton therapy has been investigated. Specifically, analyzing beam angle robustness to dose and ranges and providing fast and reliable methods for monitoring the influence of inter-fractional changes on the dose plan.
The project was carried out by Andreas Gravgaard Andersen, who is defending her/his dissertation on 2022/04/29.
The press release - ends with:
The defence is public and takes place on 2022/04/29 at 10 AM CET, at Aarhus University Hospital, Palle Juul-Jensens Boulevard 99,
Entrance C, level 1, Auditorium C114-101, DK-8200 Aarhus N., Aarhus University, Road, City. The title of the project is Strategies for evaluating and improving proton plan
robustness towards inter-fractional organ motion. For more information, please contact PhD student Andreas Gravgaard Andersen, email: andreasga22+au@gmail.com, Phone +45 3165 8140.
Assessment committee:
Professor Michael Robert Horsman (chairman and moderator of the defence) Department of Oncology (EKO), Aarhus University Hospital, Aarhus, Denmark Professor, Dr. Katia Parodi
Faculty of Physics, Ludwig Maximilians Universität, München, Germany Chief physician, Ph.D. Peter Meidahl Petersen
Department of Oncology, Rigshospitalet, Copenhagen, Denmark
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