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The 18th PhD-course in Human Cardiovascular Control Danish Cardiovascular Research Academy
The Panum Institute/Rigshospitalet, University of Copenhagen May 11th to 15th 2020
Monday 11th May Chair: Craig D. Crandall Topic: Study Design
8:30-9:00 Welcome and introduction to the program - presentation of participants and speakers, Henrik Sørensen, MD, DMSc, Niels H. Secher, MD, DMSc, Copenhagen 9:00-10:30 Integrative cardiovascular physiology: A primer to hypothesis-driven research
1. Developing the question; Mechanisms of exercise-induced cardioprotection, Peter Raven PhD, USA
2. 20 years of skin graft research – How we got to where we are, Craig G.
Crandall PhD, USA 10:30-11:00 Refreshments
11:00-11:30 Translational Research Primer: Understanding hypertension through animal and human investigation, Scott Smith PhD, USA
11:30-12:00 Lunch
12:00-14:30 Presentation of PhD-projects in groups
5 min each with expression of the hypothesis and the method(s) used.
Paul Fadel PhD, Texas, Craig D. Crandall, Peter Raven, Scott Smith and Johannes Van Lieshout MD, PhD, The Netherlands
14:30-15.00 Refreshment
15:00-15:45 Designing an experimental and clinical trial - do your homework, Anders Perner MD, PhD, Copenhagen
Dinner Bagsværd 18:00
2 Tuesday 12th May
Chair: Peter Raven
Topic: Central Circulation
8:00-9:00 Determination of cardiac output at rest and during exercise, Christoph Siebenmann PhD, Italy and Johannes Van Lieshout
9:00-10:00 Evaluation of cardiac function and myocardial perfusion by magnetic resonance Imaging, Kiril Aleksov Ahtarovski MD, PhD, Copenhagen
10:00-10:45 Arterial baroreflex control of heart rate and blood pressure, Peter B Raven 10:45-11:15 Refreshments
11:15-12:15 Workshop: Cardiac output and blood pressure at rest and during exercise – the baroreceptor reflex, Peter B Raven, James Fisher PhD, New Zealand and Johannes Van Lieshout
12:15-12:45 Lunch
12:45-14:45 Workshop: ECHO and Doppler evaluations of the heart and ultrasound assessment of peripheral circulation, Jesper Kjærgaard MD DMSc, Kim Bredahl MD,PhD, Copenhagen
14:45-16:00 Demonstration: ECMO/Flow Jesper Kjærgaard MD, DMSc, Hasse Møller Sørensen MD, Copenhagen
3 Wednesday 13th May
Chair: Johannes Van Lieshout Topic: Regional blood flow
9:00-12:00 Demonstration:
Cardiovascular regulation in the pig, Rune Strandby MD, PhD and Erika Nodin MD, Copenhagen
12:00-12:30 Lunch
12:30-13:00 Evaluation of cerebral blood flow and oxygenation, methodological considerations and clinical practice, Kirsten Møller MD, DMSc, Copenhagen 13:00-13:30 Cerebral blood flow: static and dynamic autoregulation and relation to
orthostatic stress, Johannes Van Lieshout
13:30-14:15 Why the brain needs oxygen and gravity; a (free) radical perspective, Damian Bailey PhD, UK
14:15-14:45 Refreshments
14:45-15:15 Regulation of skin blood flow and rehabilitation after burn injury, Craig G. Crandall
15:15-16:00 Initial management of burn injury, Christian O. Steensen MD, PhD, Copenhagen
4 Thursday 14th May
Chair: José González-Alonso
Topic: Blood volume and regulation of blood flow
8:00-8:45 Sympathetic activity, Paul Fadel
8:45-9:15 Methods for determination of blood flow, Lasse Glieman PhD, Copenhagen
9:15-10:00 Regulation of skeletal muscle blood flow: role of vasodilators and sympatholysis Ylva Hellsten DMSc, Copenhagen
10:00-10:30 Refreshments
10:30-11:00 The exercise pressor reflex - interaction between cardiac output and muscle metabolism and blood flow James Fisher
11:00-11:30 Determination of blood volume, Christoph Siebenmann
11:30-12:00 Maintaining central blood volume during surgery, Rune Strandby MD, PhD, Copenhagen
12:00-12:30 Lunch
12:30-13:00 Organ blood flow and metabolism, Gerrit van Hall PhD, Copenhagen
13:00-13:30 Circulation and blood volume in world class athletes, Carsten Lundby, PhD, Copenhagen
13:30-14:00 Human cardiovascular function and control during exercise and heat stress –an integrative overview, José González-Alonso PhD, UK
Course dinner
5 Friday 15th May
Chair: Henrik Sørensen Topic: Special issues
8:30-9:00 Preparing the circulation for surgery, Nicolai B. Foss MD, DMSc, Copenhagen 9:00-9:30 Cerebral blood in liver failure, Fin S Larsen MD, DMSc, PhD, Copenhagen
9:30-10:00 Mechanic support – exercise and waiting for a new heart, Finn Gustafsson MD, DMSc, Copenhagen
10:00-10:30 Refreshments
10:30-11:00 Endothelia function and coagulation in health and disease, Jakob Stensballe MD, PhD, Copenhagen
11:00-11:30 Sepsis: physiology and treatment, Anders Perner MD, PhD 11:30-12:15 Lunch
12:15-13:15 Evaluation, discussion and examination
6 Speakers:
Anders Perner Professor, MD, PhD (DK): anders.perner@regionh.dk Carsten Lundby Professor, MD, PhD (DK): Carsten.lundby@regionh.dk
Christian O. Steensen MD, PhD (DK): Christian.overgaard.steensen@regionh.dk Christoph Siebenmann PhD (IT): Christoph.Siebenmann@eurac.edu
Craig G. Crandall Professor, PhD (US): craigcrandall@texashealth.org Damian Bailey Professor, PhD, (UK): damian.bailey@southwales.ac.uk Erika Nordin MD (DK): erika.helena.ingegerd.nodin@regionh.dk
Fin Stolze Larsen Professor, MD, DMSc, PhD (DK): fin.stolze.larsen@regionh.dk Finn Gustafsson Professor, MD, DMSc (DK): finn.gustafsson@regionh.dk
Gerrit van Hall Professor, PhD (DK):Gerrit.Van.Hall@regionh.dk
Hasse Møller Sørensen, MD (DK): peter.hasse.moeller-soerensen@regionh.dk Henrik Sørensen Ass. Professor, MD, DMSc (DK): hs770@hotmail.com
Jakob Stensballe MD, PhD (DK): jakob.stensballe@regionh.dk James Fisher Professor, PhD (NZ): jp.fisher@auckland.ac.nz Jesper Kjærgaard MD DMSc (DK): jesper.kjaergaard@regionh.dk
Johannes Van Lieshout Professor, MD, PhD (NL): jjvanlieshout@gmail.com José González-Alonso Professor, PhD (UK): Jose.Gonzalez-Alonso@brunel.ac.uk Kim Bredahl MD, PhD (DK): kim.kargaard.bredahl@regionh.dk
Kirsten Møller Professor, MD, DMSc (DK): kirsten.moeller.01@regionh.dk Kiril Aleksov Ahtarovski MD, PhD (DK): kiril.aleksov.ahtarovski@regionh.dk Lasse Glieman Assoc. Professor, PhD (DK): gliemann@nexs.ku.dk
Nicolai B. Foss Assoc. Professor, MD, DMSc (DK): Nicolai.bang.foss@regionh.dk Niels H. Secher Professor, MD, DMSc (DK): niels.secher@regionh.dk
Paul Fadel Professor, PhD (US):paul.fadel@uta.edu
Peter Raven Professor, PhD (US): Peter.Raven@unthsc.edu
Rune Strandby MD, PhD (DK): rune.broni.strandby.01@regionh.dk Scott Smith Professor, PhD (US): Scott.Smith@UTSouthwestern.edu Ylva Hellsten Professor, DMSc (DK): yhellsten@nexs.ku.dk
